Article
Potentially functional variants of ERRFI1 in hypoxia-related genes predict survival of non-small cell lung cancer patients.
Cancer medicine - 1 Aug 2024
Wang Huilin, Liu Hongliang, Lu Guojun, Tang Xiaozhun, Luo Sheng, Du Mulong, Christiani David C, Wei Qingyi
Abstract excerpt
BACKGROUND: Hypoxia is often involved in tumor microenvironment, and the hypoxia-induced signaling pathways play a key role in aggressive cancer phenotypes, including angiogenesis, immune evasion, and therapy resistance. However, it is unknown what role genetic variants in the hypoxia-related genes play in survival of patients with non-small cell lung cancer (NSCLC). METHODS: We evaluated the associations between...
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