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Article

Potentially functional variants of ERAP1, PSMF1 and NCF2 in the MHC-I-related pathway predict non-small cell lung cancer survival.

Cancer immunology, immunotherapy : CII - 1 Oct 2021

Yang Sen, Tang Dongfang, Zhao Yu Chen, Liu Hongliang, Luo Sheng, Stinchcombe Thomas E, Glass Carolyn, Su Li, Shen Sipeng, Christiani David C, Wang Qiming, Wei Qingyi

Abstract excerpt

BACKGROUND: Cellular immunity against tumor cells is highly dependent on antigen presentation by major histocompatibility complex class I (MHC-I) molecules. However, few published studies have investigated associations between functional variants of MHC-I-related genes and clinical outcomes of lung cancer patients. METHODS: We performed a two-phase Cox proportional hazards regression analysis by using two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33651148
DOI: 10.1007/s00262-021-02877-9
PMCID: PMC8410895

Genes

ERAP1
PSMF1
NCF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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