Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulatory variants in cancer-related pathway genes predict survival of patients with surgically resected non-small cell lung cancer.

Gene - 10 Mar 2018

Shin Kyung Min, Hong Mi Jeong, Lee Shin Yup, Jin Cheng Cheng, Baek Sun Ah, Lee Jang Hyuck, Choi Jin Eun, Kang Hyo-Gyoung, Lee Won Kee, Seok Yangki, Lee Eung Bae, Jeong Ji Yun, Yoo Seung Soo, Lee Jaehee, Cha Seung Ick, Kim Chang Ho, Kim Young Chul, Oh In Jae, Na Kook Joo, Cho Sukki, Jheon Sanghoon, Park Jae Yong

Abstract excerpt

BACKGROUND: We conducted this study to identify genetic variants in cancer-related pathway genes which can predict prognosis of NSCLC patients after surgery, using a comprehensive list of regulatory single nucleotide polymorphisms (SNPs) prioritized by RegulomeDB. METHOD: A total of 509 potentially functional SNPs in cancer-related pathway genes selected from RegulomeDB were evaluated. These SNPs were analyzed in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Computational Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Lung Neoplasms

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Share to Survival Analysis

Share to Treatment Outcome

Source

Identifiers

PMID: 29289609
DOI: 10.1016/j.gene.2017.12.055

Genes

BRCA2
ERCC1
LTBP4
NELFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulatory variants in cancer-related pathway genes predict survival of patients with surgically resected non-small cell lung cancer.PMID 29289609Read ↗

Functional intronic ERCC1 polymorphism from regulomeDB can predict survival in lung cancer after surgery.Semantic proximity Read ↗

Intronic variant of EGFR is associated with GBAS expression and survival outcome of early-stage non-small cell lung cancer.Semantic proximity Read ↗

Pathway-based analysis using genome-wide association data from a Korean non-small cell lung cancer study.Semantic proximity Read ↗

RACK1 is a candidate gene associated with the prognosis of patients with early stage non-small cell lung cancer.Semantic proximity Read ↗

Potentially functional genetic variants in the TNF/TNFR signaling pathway genes predict survival of patients with non‐small cell lung cancer in the PLCO cancer screening trialSemantic proximity Read ↗

A mRNA-miRNA-lncRNA regulatory network related to potential pathogenesis and prognostic markers of Non- small cell lung cancerSemantic proximity Read ↗

Potentially functional polymorphisms in DNA repair genes and non-small-cell lung cancer survival: a pathway-based analysis.Semantic proximity Read ↗

Potentially functional genetic variants in the c-Myb signaling pathway genes are associated with survival of non-small cell lung cancer patients in the PLCO Cancer Screening TrialSemantic proximity Read ↗

Polymorphisms in cancer-related pathway genes and lung cancer.Semantic proximity Read ↗

Identification and Validation of an RNA Binding Proteins-Associated Prognostic Signature for Non-Small Cell Lung CancerSemantic proximity Read ↗

Integrating expression-related SNPs into genome-wide gene- and pathway-based analyses identified novel lung cancer susceptibility genes.Semantic proximity Read ↗

Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.