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Article

Polymorphisms of HIF1A gene are associated with prognosis of early stage non-small-cell lung cancer patients after surgery.

Medical oncology (Northwood, London, England) - 1 Apr 2014

Liu Boya, Liu Qingchun, Song Yang, Li Xiaofei, Wang Yunjie, Wan Shaogui, Zhang Zhipei, Su Haichuan

Abstract excerpt

Hypoxia-inducible factor 1α (HIF1α) activates the transcription of genes that are involved in angiogenesis and cell survival. Over-expression of HIF1α caused by intratumoral hypoxia and its genetic alterations are associated with increased mortality in several cancer types including non-small-cell lung cancer (NSCLC). The aim of this study was to investigate the predictive role of single nucleotide polymorphisms...

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Source

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Identifiers

PMID: 24567056
DOI: 10.1007/s12032-014-0877-8
PMCID: PMC3971443

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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