Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients.

Translational research : the journal of laboratory and clinical medicine - 1 Jul 2021

Wu Yufeng, Liu Zhensheng, Tang Dongfang, Liu Hongliang, Luo Sheng, Stinchcombe Thomas E, Glass Carolyn, Su Li, Lin Lijuan, Christiani David C, Wang Qiming, Wei Qingyi

Abstract excerpt

The gonadotropin-releasing hormone (GnRH) signaling pathway controls reproductive functions and cancer growth and progression. However, few studies investigated roles of genetic variants of GnRH pathway genes in survival of patients with non-small cell lung cancer (NSCLC). Therefore, we first evaluated associations between 22,528 single-nucleotide polymorphisms (SNPs) in 101 GnRH pathway genes and survival of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gonadotropin-Releasing Hormone

Share to Heparin-binding EGF-like Growth Factor

Share to Inositol 1,4,5-Trisphosphate Receptors

Share to Kaplan-Meier Estimate

Share to Translational Research, Biomedical

Source

Open in PubMed Open full text

Identifiers

PMID: 33400994
DOI: 10.1016/j.trsl.2020.12.009
PMCID: PMC8184605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients.PMID 33400994Read ↗

Potentially functional genetic variants in the TNF/TNFR signaling pathway genes predict survival of patients with non‐small cell lung cancer in the PLCO cancer screening trialSemantic proximity Read ↗

Potentially functional genetic variants in the c-Myb signaling pathway genes are associated with survival of non-small cell lung cancer patients in the PLCO Cancer Screening TrialSemantic proximity Read ↗

Potentially functional variants of ERRFI1 in hypoxia-related genes predict survival of non-small cell lung cancer patients.Semantic proximity Read ↗

Genome-Wide Splicing Quantitative Expression Locus Analysis Identifies Causal Risk Variants for Non-Small Cell Lung Cancer.Semantic proximity Read ↗

Regulatory variants in cancer-related pathway genes predict survival of patients with surgically resected non-small cell lung cancer.Semantic proximity Read ↗

Germline Polymorphisms Associated with Overall Survival in Lung Adenocarcinoma: Genome-Wide AnalysisSemantic proximity Read ↗

Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study.Semantic proximity Read ↗

Potentially functional variants of ERAP1, PSMF1 and NCF2 in the MHC-I-related pathway predict non-small cell lung cancer survival.Semantic proximity Read ↗

Intronic variant of EGFR is associated with GBAS expression and survival outcome of early-stage non-small cell lung cancer.Semantic proximity Read ↗

Potentially functional polymorphisms in DNA repair genes and non-small-cell lung cancer survival: a pathway-based analysis.Semantic proximity Read ↗

Genome-wide association study of genetic predictors of overall survival for non-small cell lung cancer in never smokers.Semantic proximity Read ↗

Prospective Germline Exome and Machine Learning-Based Risk Score Identify Predictive and PrognosticBiomarkers of Immunotherapy Outcomes in Advanced Non-Small Cell Lung CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.