Article
Long-term stability of acquired drug resistance and resistance associated mutations in the fungal pathogen Nakaseomyces glabratus (Candida glabrata).
Frontiers in cellular and infection microbiology - 1 Jan 2024
Ksiezopolska Ewa, Schikora-Tamarit Miquel Àngel, Carlos Nunez-Rodriguez Juan, Gabaldón Toni
Abstract excerpt
The limited number of available antifungal drugs and the increasing number of fungal isolates that show drug or multidrug resistance pose a serious medical threat. Several yeast pathogens, such as Nakaseomyces glabratus (Candida glabrata), show a remarkable ability to develop drug resistance during treatment through the acquisition of genetic mutations. However, how stable this resistance and the underlying...
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