Article
Population dynamics and the evolution of antifungal drug resistance in Candida albicans.
FEMS microbiology letters - 1 Aug 2012
Huang Mian, Kao Katy C
Abstract excerpt
Candida albicans is an important human fungal pathogen. Resistance to all major antifungal agents has been observed in clinical isolates of Candida spp. and is a major clinical challenge. The rise and expansion of drug-resistant mutants during exposure to antifungal agents occurs through a process of adaptive evolution, with potentially complex population dynamics. Understanding the population dynamics during the...
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