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The Microevolution of Antifungal Drug Resistance in Pathogenic Fungi

13 Nov 2023

Abstract excerpt

The mortality rates of invasive fungal infections remain high because of the limited number of antifungal drugs available and antifungal drug resistance, which can rapidly evolve during treatment. Mutations in key resistance genes such as ERG11 were postulated to be the predominant cause of antifungal drug resistance in the clinic. However, recent advances in whole genome sequencing have revealed that there are...

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PMID: 38004768
DOI: 10.3390/microorganisms11112757

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