Article
In-host microevolution of Aspergillus fumigatus: A phenotypic and genotypic analysis.
Fungal genetics and biology : FG & B - 1 Apr 2018
Ballard Eloise, Melchers Willem J G, Zoll Jan, Brown Alistair J P, Verweij Paul E, Warris Adilia
Abstract excerpt
In order to survive, Aspergillus fumigatus must adapt to specific niche environments. Adaptation to the human host includes modifications facilitating persistent colonisation and the development of azole resistance. The aim of this study is to advance understanding of the genetic and physiological adaptation of A. fumigatus in patients during infection and treatment. Thirteen A. fumigatus strains were isolated...
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