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Article

Summary data-based Mendelian randomization and single-cell RNA sequencing analyses identify immune associations with low-level LGALS9 in sepsis.

Journal of cellular and molecular medicine - 1 Jul 2024

Yang Yongsan, Dong Lei, Li Yanguo, Huang Ye, Zeng Xiaoxi

Abstract excerpt

Sepsis is one of the major challenges in intensive care units, characterized by the complexity of the host immune status. To gain a deeper understanding of the pathogenesis of sepsis, it is crucial to study the phenotypic changes in immune cells and their underlying molecular mechanisms. We conducted Summary data-based Mendelian randomization analysis by integrating genome-wide association studies data for sepsis...

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Identifiers

PMID: 39044269
DOI: 10.1111/jcmm.18559
PMCID: PMC11265992

Genes

LGALS9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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