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Integration of Mendelian Randomization to Explore the Genetic Influences of Pediatric Sepsis: A Focus on RGL4, ATP9A, MAP3K7CL, and DDX11L2

2024-04-11

Abstract excerpt

<title>Abstract</title> <p><bold>This study delves into the genetic underpinnings of pediatric sepsis, focusing on the association and potential mechanisms of action of four key genes: RGL4, ATP9A, MAP3K7CL, and DDX11L2. Utilizing a combination of differential expression analysis, Mendelian Randomization (MR), immune cell infiltration analysis, and validation through independent datasets, we aimed to elucidate th...

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Literature Corpus work
af226c94-803d-59b2-859f-5466667d21b2
DOI
10.21203/rs.3.rs-4173913/v1
Open publication

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Integration of Mendelian Randomization to Explore the Genetic Influences of Pediatric Sepsis: A Focus on RGL4, ATP9A, MAP3K7CL, and DDX11L2DOI 10.21203/rs.3.rs-4173913/v1
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