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THE RELATIONSHIP BETWEEN CIRCULATING IMMUNE CELL PHENOTYPES AND SEPSIS: A MENDELIAN RANDOMIZATION STUDY.

Shock (Augusta, Ga.) - 1 Apr 2024

Liu Hongmei, Liu Hai, Zhou Li, Wen Shu, Liu Tiankuang, Ju Linqin, Liu Yiwen

Abstract excerpt

ABSTRACT: Objective: The role of immune cells in sepsis remains unclear, and there is some controversy. Here, we aim to systematically assess whether distinct immune cell phenotypes impact the susceptibility to sepsis. Methods: In this study, we harnessed publicly available summary-level data from genome-wide association studies (GWASs). The selection of genetic variations strongly associated with 731 phenotypes...

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PMID: 38517244
DOI: 10.1097/SHK.0000000000002334

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