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Article

Mendelian randomization studies: a review of the approaches used and the quality of reporting.

International journal of epidemiology - 1 Apr 2015

Boef Anna G C, Dekkers Olaf M, le Cessie Saskia

Abstract excerpt

BACKGROUND: Mendelian randomization (MR) studies investigate the effect of genetic variation in levels of an exposure on an outcome, thereby using genetic variation as an instrumental variable (IV). We provide a meta-epidemiological overview of the methodological approaches used in MR studies, an...

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Identifiers

PMID: 25953784
DOI: 10.1093/ije/dyv071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25953784-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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