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Article

Human brain proteome-wide association study provides insights into the genetic components of protein abundance in obesity.

International journal of obesity (2005) - 1 Nov 2024

Zhao Qi-Gang, Song Zi-Tong, Ma Xin-Ling, Xu Qian, Bu Fan, Li Kuan, Zhang Lei, Pei Yu-Fang

Abstract excerpt

BACKGROUNDS: Genome-wide association studies have identified multiple genetic variants associated with obesity. However, most obesity-associated loci were waiting to be translated into new biological insights. Given the critical role of brain in obesity development, we sought to explore whether obesity-associated genetic variants could be mapped to brain protein abundances. METHODS: We performed proteome-wide...

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PMID: 39025989
DOI: 10.1038/s41366-024-01592-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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