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Article

A Complex Network of Obesity-Risk Genes Revealed by Systematic Bioinformatics and Single-Cell Transcriptomic Analyses.

Journal of obesity - 1 Jan 2025

Liu Yuenan, Yuan Haolin, Hu Junhui, Xu Xu, Yin Shankai, Hu Yiming, Liu Feng

Abstract excerpt

The development of obesity is closely linked to genetic factors. Despite the identification of numerous genes associated with an increased risk of obesity in humans, a comprehensive understanding of their biological roles has not been achieved. In our extensive bioinformatics study, we identified 802 core genes implicated in obesity. Our protein-protein interaction (PPI) network analysis revealed that these genes...

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Adipose Tissue
Computational Biology
Gene Expression Profiling
Gene Regulatory Networks
Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Interaction Maps

Single-Cell Analysis

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PMID: 40201036
DOI: 10.1155/jobe/7821115
PMCID: PMC11976034

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