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Article

Computational analyses of obesity associated loci generated by genome-wide association studies.

PloS one - 1 Jan 2018

Cheng Mengrong, Mei Bing, Zhou Qian, Zhang Manling, Huang Han, Han Lanchun, Huang Qingyang

Abstract excerpt

OBJECTIVES: Genome-wide association studies (GWASs) have discovered associations of numerous SNPs and genes with obesity. However, the underlying molecular mechanisms through which these SNPs and genes affect the predisposition to obesity remain not fully understood. Aims of our study are to comprehensively characterize obesity GWAS SNPs and genes through computational approaches. METHODS: For obesity GWAS...

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Gene Ontology
Genome-Wide Association Study
Genomics
MicroRNAs
Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphorylation

Polymorphism, Single Nucleotide

Protein Interaction Maps

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PMID: 29966015
DOI: 10.1371/journal.pone.0199987
PMCID: PMC6028139

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