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Characterization of the polymyxin B resistome of Pseudomonas aeruginosa.

Antimicrobial agents and chemotherapy - 1 Jan 2013

Fernández Lucía, Alvarez-Ortega Carolina, Wiegand Irith, Olivares Jorge, Kocíncová Dana, Lam Joseph S, Martínez José Luis, Hancock Robert E W

Abstract excerpt

Multidrug resistance in Pseudomonas aeruginosa is increasingly becoming a threat for human health. Indeed, some strains are resistant to almost all currently available antibiotics, leaving very limited choices for antimicrobial therapy. In many such cases, polymyxins are the only available option, although as their utilization increases so does the isolation of resistant strains. In this study, we screened a...

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PMID: 23070157
DOI: 10.1128/AAC.01583-12
PMCID: PMC3535977

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