Article
Characterization of the polymyxin B resistome of Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy - 1 Jan 2013
Fernández Lucía, Alvarez-Ortega Carolina, Wiegand Irith, Olivares Jorge, Kocíncová Dana, Lam Joseph S, Martínez José Luis, Hancock Robert E W
Abstract excerpt
Multidrug resistance in Pseudomonas aeruginosa is increasingly becoming a threat for human health. Indeed, some strains are resistant to almost all currently available antibiotics, leaving very limited choices for antimicrobial therapy. In many such cases, polymyxins are the only available option...
Topics
- Anti-Bacterial Agents
- Cell Membrane
- Cell Membrane Permeability
- DNA Transposable Elements
- Drug Resistance, Bacterial
- Gene Library
- Genes, Bacterial
- Lipopolysaccharides
- Mutation
- Polymyxin B
- Pseudomonas aeruginosa
- Transcriptome