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Article

The neglected intrinsic resistome of bacterial pathogens.

PloS one - 20 Feb 2008

Fajardo Alicia, Martínez-Martín Nadia, Mercadillo María, Galán Juan C, Ghysels Bart, Matthijs Sandra, Cornelis Pierre, Wiehlmann Lutz, Tümmler Burkhard, Baquero Fernando, Martínez José L

Abstract excerpt

Bacteria with intrinsic resistance to antibiotics are a worrisome health problem. It is widely believed that intrinsic antibiotic resistance of bacterial pathogens is mainly the consequence of cellular impermeability and activity of efflux pumps. However, the analysis of transposon-tagged Pseudomonas aeruginosa mutants presented in this article shows that this phenotype emerges from the action of numerous...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18286176
DOI: 10.1371/journal.pone.0001619
PMCID: PMC2238818

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Source receipt: pubmed, retrieved 7 Sept 2026.

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