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Article

Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa.

Scientific reports - 28 Apr 2014

Le Shuai, Yao Xinyue, Lu Shuguang, Tan Yinling, Rao Xiancai, Li Ming, Jin Xiaolin, Wang Jing, Zhao Yan, Wu Nicholas C, Lux Renate, He Xuesong, Shi Wenyuan, Hu Fuquan

Abstract excerpt

Bacteria develop a broad range of phage resistance mechanisms, such as prevention of phage adsorption and CRISPR/Cas system, to survive phage predation. In this study, Pseudomonas aeruginosa PA1 strain was infected with lytic phage PaP1, and phage-resistant mutants were selected. A high percentage (~30%) of these mutants displayed red pigmentation phenotype (Red mutant). Through comparative genomic analysis, one...

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Share to Bacteriophages
Share to Chromosomes, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genome, Bacterial

Share to Pancreatitis-Associated Proteins

Share to Pigments, Biological

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Share to Pseudomonas Infections

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Identifiers

PMID: 24770387
DOI: 10.1038/srep04738
PMCID: PMC4001099

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