Article
Causal impact of statins on susceptibility to osteoarthritis: insights from a two-sample Mendelian randomization analysis.
International journal of clinical pharmacy - 1 Oct 2024
Yu Kefu, Li Ziming, Shi Weizhong, Zhao Zhigang, Yang Li
Abstract excerpt
BACKGROUND: Osteoarthritis is a widely prevalent cause of pain and disability among older adults. It is an incurable condition, and most treatments are aimed at alleviating symptoms. AIM: This study aimed to investigate the impact of statins on osteoarthritis by using a two-sample Mendelian randomization approach, using genetic variants associated with statin use as instrumental variables. METHOD: Information on...
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