Article
Mendelian Randomization Studies of Lifestyle-Related Risk Factors for Osteoarthritis: A PRISMA Review and Meta-Analysis.
International journal of molecular sciences - 7 Oct 2022
Ho Justin, Mak Christopher Chi Hang, Sharma Vivek, To Kendrick, Khan Wasim
Abstract excerpt
Risk factors for osteoarthritis (OA) often exert effects over protracted time-courses. Mendelian randomization (MR) studies therefore have an advantage over conventional observational studies when studying the causal effect of long-term lifestyle-related risk factors on OA. However, given the heterogeneous design of existing MR studies on OA, the reported causal estimates of these effects remain inconsistent,...
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