Article
Emergence and fixation of SARS-CoV-2 minority variants in a chronically infected patient receiving therapy in Denmark.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Oct 2024
Fonager Jannik, Nytofte Nikolaj Julian Skrøder, Schouw Christian Højte, Poulsen Christian B, Wiese Lothar, Fomsgaard Anders, Bennedbæk Marc, Rasmussen Morten, Nielsen Xiaohui Chen
Abstract excerpt
SARS-CoV-2 variants of concern (VOC), such as Delta and Omicron have harbored mutations, which increased viral infectivity or ability to evade neutralizing antibodies. Immunocompromised patients might be a source of some of these emerging variants. In this study, we sequenced 17 consecutive samples from an immunocompromised patient with a long-term SARS-CoV-2 infection with the pre-VOC era lineage B.1.177.35. We...
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