Article
DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenes
17 Jun 2019
Abstract excerpt
DNA methylation is pervasive across all domains of life. In bacteria, the presence of N6-methyladenosine (m6A) has been detected among diverse species, yet the contribution of m6A to the regulation of gene expression is unclear in many organisms. Here we investigated the impact of DNA methylation on gene expression and virulence within the human pathogen Streptococcus pyogenes, or Group A Streptococcus. Single...
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