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Influenza A virus modulation of <i>Streptococcus pneumoniae</i> infection using ex vivo transcriptomics in a human primary lung epithelial cell model reveals differential host glycoconjugate uptake and metabolism

2023-01-30

Abstract excerpt

<h4>Background</h4> Streptococcus pneumoniae (Spn) is typically an asymptomatic colonizer of the nasopharynx but it also causes pneumonia and disseminated disease affecting various host anatomical sites. Transition from colonization to invasive disease is not well understood. Studies have shown that such a transition can occur as result of influenza A virus coinfection. <h4>Methods</h4> We investigated the pneu...

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Literature Corpus work
6612d722-f031-5104-8cff-91e2484c3efe
DOI
10.1101/2023.01.29.526157
Open publication

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