Article
Investigating the role of killer cell immunoglobulin-like receptors and human leukocyte antigen genetic variants in hepatitis C virus infection.
Journal of medical virology - 1 Jul 2024
Li Yuwen, Zeng Tian, Huang Peng, Tan Weilong, Feng Yue, Xia Xueshan, Feng Zepei, Shen Chao, Fan Haozhi, Zhu Chuanlong, Yin Wen, Qian Liqin, Ren Chengrui, Yue Ming
Abstract excerpt
The genetic diversity of killer cell immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) genes influences the host's immune response to viral pathogens. This study aims to explore the impact of five single nucleotide polymorphisms (SNPs) in KIR3DL2 and HLA-A genes on hepatitis C virus (HCV) infection. A total of 2251 individuals were included in the case-control study. SNPs including KIR3DL2...
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