Article
Genetic (KIR, HLA-C) and Some Clinical Parameters Influencing the Level of Liver Enzymes and Early Virologic Response in Patients with Chronic Hepatitis C.
Archivum immunologiae et therapiae experimentalis - 1 Feb 2016
Mozer-Lisewska Iwona, Zwolińska Katarzyna, Kowala-Piaskowska Arleta Elżbieta, Bura Maciej, Rozpłochowski Błażej, Pauli Anna, Żeromski Jan, Piasecki Egbert, Kuśnierczyk Piotr
Abstract excerpt
Natural killer cells play an important role as effectors of innate immunity and regulators of adaptive immunity. They are important elements of the innate response to viral infections, which they detect using human leukocyte antigen (HLA) class I-binding receptors. Most polymorphic of these are killer cell immunoglobulin-like receptors (KIRs) which exist as two basic isotypes, activating or inhibitory receptors...
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