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Article

Diversity of killer cell immunoglobulin-like receptor (KIR) genotypes and KIR2DL2/3 variants in HCV treatment outcome.

PloS one - 1 Jan 2014

Vidal-Castiñeira Jose Ramón, López-Vázquez Antonio, Martínez-Borra Jesús, Martínez-Camblor Pablo, Prieto Jesús, López-Rodríguez Rosario, Sanz-Cameno Paloma, de la Vega Juan, Rodrigo Luis, Pérez-López Rosa, Pérez-Álvarez Ramón, López-Larrea Carlos

Abstract excerpt

The aim of this study was to analyse the distribution of KIR haplotypes and the KIR2DL2/3 alleles in chronic HCV-infected patients in order to establish the influence on the response to pegylated interferon plus ribavirin classical treatment. The alleles study of previously associated KIR2DL2/3 showed that KIR2DL2*001 was more frequent in non-SVR (NSVR) (42.2% vs. 27.5%, p<0.05) and KIR2DL3*001 was associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24927414
DOI: 10.1371/journal.pone.0099426
PMCID: PMC4057177

Genes

IFNL3

Provenance

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