Article
Impact of KIR3DL1/3DS1 and HLA-B polymorphisms on hepatitis C virus infection: a case-control study.
Frontiers in cellular and infection microbiology - 1 Jan 2026
Yin Wen, Zeng Tian, Ren Chengrui, Chen Yuting, Guo Yue, Ma Kexin, Zhang Yun, Yu Rongbin, Wang Chongcai, Cui Jizheng, Huang Peng, Yue Ming
Abstract excerpt
The polymorphism of killer-cell immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) genes determines the host's susceptibility to viral infections. This study aimed to investigate the impact of five single nucleotide polymorphisms (SNPs) in KIR3DL1/3DS1 and HLA-B genes on hepatitis C virus (HCV) infection. A total of 1881 individuals participated in this case-control study. SNPs including...
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