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Article

Associations of E-proteinoid 3 receptor genetic polymorphisms with salt sensitivity, longitudinal blood pressure changes, and hypertension incidence in Chinese adults.

Journal of clinical hypertension (Greenwich, Conn.) - 1 Aug 2024

Chang Ming-Ke, Wu Guan-Ji, Bao Peng, Yao Shi, Du Ming-Fei, Chu Chao, Wang Dan, Jia Hao, Sun Yue, Yan Yu, Zhang Xi, Hu Gui-Lin, Man Zi-Yue, Guo Tong-Shuai, Luo Wen-Jing, Li Hao, Wang Yang, Mu Jian-Jun

Abstract excerpt

The E-proteinoid 3 receptor (PTGER3), a member of the prostaglandin E2 (PGE2) subtype receptor, belongs to the G-protein-coupled superfamily of receptors. Animal studies have demonstrated its involvement in salt sensitivity by regulating sodium reabsorption. This study aimed to investigate the association between genetic variants of PTGER3 and salt sensitivity, longitudinal blood pressure (BP) changes, and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38952049
DOI: 10.1111/jch.14859
PMCID: PMC11301432

Genes

PTGER3
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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