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Article

Association of plasma cyclooxygenase-2 levels and genetic polymorphisms with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults.

Journal of hypertension - 1 Sept 2020

Wang Yang, Zhou Qing, Gao Wei-Hua, Yan Yu, Chu Chao, Chen Chen, Yuan Yue, Wang Ke-Ke, Ma Qiong, Gao Ke, Hu Jia-Wen, Liao Yue-Yuan, Li Min, Sun Yue, Chang John, Zhang Jie, Xu Jing-Tao, Wang Dan, Zang Wei-Jin, Mu Jian-Jun

Abstract excerpt

OBJECTIVE: Cyclooxygenase (COX)-2, an inducible isoform of the major rate-limiting enzymes that regulate the production of prostaglandins is associated with injury, inflammation and proliferation. We sought to examine whether plasma COX-2 levels and its genetic variants is associated with salt sensitivity, BP changes and/or hypertension in humans. METHODS: Eighty participants (aged 18-65 years) were maintained...

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Identifiers

PMID: 32516287
DOI: 10.1097/HJH.0000000000002473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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