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Article

The role of the kallikrein-kinin system genes in the salt sensitivity of blood pressure: the GenSalt Study.

American journal of epidemiology - 1 Oct 2012

Gu Dongfeng, Zhao Qi, Kelly Tanika N, Hixson James E, Rao Dabeeru C, Cao Jie, Chen Jing, Li Jianxin, Chen Jichun, Ji Xu, Hu Dongsheng, Wang Xushan, Liu De-Pei, He Jiang

Abstract excerpt

The current study comprehensively examined the association between common genetic variants of the kallikrein-kinin system (KKS) and blood pressure salt sensitivity. A 7-day low-sodium followed by a 7-day high-sodium dietary intervention was conducted among 1,906 Han Chinese participants recruited from 2003 to 2005. Blood pressure was measured by using a random-zero sphygmomanometer through the study. A total of...

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Identifiers

PMID: 23035147
DOI: 10.1093/aje/kws277
PMCID: PMC3530362

Genes

BDKRB2
ECE1

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