Article
Associations of corin genetic polymorphisms with salt sensitivity, blood pressure changes, and hypertension incidence in Chinese adults.
Journal of clinical hypertension (Greenwich, Conn.) - 1 Dec 2021
Zou Ting, Yao Shi, Du Ming-Fei, Mu Jian-Jun, Chu Chao, Hu Gui-Lin, Liao Yue-Yuan, Chen Chen, Wang Dan, Ma Qiong, Yan Yu, Jia Hao, Wang Ke-Ke, Sun Yue, Niu Ze-Jiaxin, Zhang Xi, Yan Rui-Chen, Man Zi-Yue, Ren Dan-Feng, Wang Lan, Gao Wei-Hua, Li Hao, Wu Yong-Xing, Li Chun-Hua, Gao Ke, Zhang Jie, Yang Tie-Lin, Wang Yang
Abstract excerpt
Corin, a transmembrane serine protease that can cleave pro-atrial natriuretic peptide (Pro-ANP) into smaller bioactive molecule atrial natriuretic peptide, has been shown to be involved in the pathophysiology of hypertension, cardiac hypertrophy. We sought to examine the associations of corin genetic variations with salt sensitivity, blood pressure (BP) changes and hypertension incidence. We studied participants...
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