Article
Associations of SGLT2 genetic polymorphisms with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jul 2023
Jia Hao, Bao Peng, Yao Shi, Zhang Xi, Mu Jian-Jun, Hu Gui-Lin, Du Ming-Fei, Chu Chao, Zhang Xiao-Yu, Wang Lan, Liao Yue-Yuan, Wang Dan, Ma Qiong, Yan Yu, Niu Ze-Jiaxin, Gao Wei-Hua, Li Hao, Wu Guan-Ji, Chang John, Wang Yang
Abstract excerpt
Sodium-glucose cotransporter 2 (SGLT2) inhibitors lowers blood pressure (BP) and exert a salutary effect on the salt sensitivity of BP. This study aimed to examine the associations of SGLT2 genetic variants with salt sensitivity, longitudinal BP changes and the risk of incident hypertension in Baoji Salt-Sensitive Study. A total of 514 participants were recruited when the cohort was established in 2004, and 333...
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