Article
Genome-wide linkage and positional candidate gene study of blood pressure response to dietary potassium intervention: the genetic epidemiology network of salt sensitivity study.
Circulation. Cardiovascular genetics - 1 Dec 2010
Kelly Tanika N, Hixson James E, Rao Dabeeru C, Mei Hao, Rice Treva K, Jaquish Cashell E, Shimmin Lawrence C, Schwander Karen, Chen Chung-Shuian, Liu Depei, Chen Jichun, Bormans Concetta, Shukla Pramila, Farhana Naveed, Stuart Colin, Whelton Paul K, He Jiang, Gu Dongfeng
Abstract excerpt
BACKGROUND: Genetic determinants of blood pressure (BP) response to potassium, or potassium sensitivity, are largely unknown. We conducted a genome-wide linkage scan and positional candidate gene analysis to identify genetic determinants of potassium sensitivity. METHODS AND RESULTS: A total of 1906 Han Chinese participants took part in a 7-day high-sodium diet followed by a 7-day high-sodium plus potassium...
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