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Article

Associations of Genetic Variations in the NR3C2 With Salt Sensitivity, Longitudinal Blood Pressure Changes, and Incidence of Hypertension in Chinese Adults.

Journal of clinical hypertension (Greenwich, Conn.) - 1 Sept 2025

Wang Lan, Chang Ming-Ke, Yue Xue-Mei, Guo Yan-Jie, Yao Yan-Ni, Liu Nai-Rong, Yang Bei-Bei, Niu Ze-Jiaxin, Gao Wei-Hua, Li Hao, Wang Yang

Abstract excerpt

Nuclear receptor subfamily 3 group C member 2 (NR3C2) encodes the mineralocorticoid receptor (MR), which plays a pivotal role in the regulation of electrolyte and fluid homeostasis by mediating the physiological actions of mineralocorticoids, primarily aldosterone. In this study, we analyzed data from the Baoji Salt-Sensitivity Study, a population-based dietary intervention conducted in 2004 in northern China. A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40932182
DOI: 10.1111/jch.70137
PMCID: PMC12424066

Genes

NR3C2
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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