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Article

Canonical and noncanonical roles of Hop1 are crucial for meiotic prophase in the fungus Sordaria macrospora.

PLoS biology - 1 Jul 2024

Dubois Emeline, Boisnard Stéphanie, Bourbon Henri-Marc, Yefsah Kenza, Budin Karine, Debuchy Robert, Zhang Liangran, Kleckner Nancy, Zickler Denise, Espagne Eric

Abstract excerpt

We show here that in the fungus Sordaria macrospora, the meiosis-specific HORMA-domain protein Hop1 is not essential for the basic early events of chromosome axis development, recombination initiation, or recombination-mediated homolog coalignment/pairing. In striking contrast, Hop1 plays a critical role at the leptotene/zygotene transition which is defined by transition from pairing to synaptonemal complex (SC)...

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Identifiers

PMID: 38950075
DOI: 10.1371/journal.pbio.3002705
PMCID: PMC11244814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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