Article
Meiotic double-strand breaks at the interface of chromosome movement, chromosome remodeling, and reductional division.
Genes & development - 1 Nov 2003
Storlazzi Aurora, Tessé Sophie, Gargano Silvana, James Françoise, Kleckner Nancy, Zickler Denise
Abstract excerpt
Chromosomal processes related to formation and function of meiotic chiasmata have been analyzed in Sordaria macrospora. Double-strand breaks (DSBs), programmed or gamma-rays-induced, are found to promote four major events beyond recombination and accompanying synaptonemal complex formation: (1) juxtaposition of homologs from long-distance interactions to close presynaptic coalignment at midleptotene; (2)...
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