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Article

Joint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosis.

PLoS genetics - 1 Jan 2013

O'Neil Nigel J, Martin Julie S, Youds Jillian L, Ward Jordan D, Petalcorin Mark I R, Rose Anne M, Boulton Simon J

Abstract excerpt

The generation and resolution of joint molecule recombination intermediates is required to ensure bipolar chromosome segregation during meiosis. During wild type meiosis in Caenorhabditis elegans, SPO-11-generated double stranded breaks are resolved to generate a single crossover per bivalent and the remaining recombination intermediates are resolved as noncrossovers. We discovered that early recombination...

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Identifiers

PMID: 23874209
DOI: 10.1371/journal.pgen.1003582
PMCID: PMC3715453

Genes

BLM
GEN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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