Article
Mnd1/Hop2 facilitates Dmc1-dependent interhomolog crossover formation in meiosis of budding yeast.
Molecular and cellular biology - 1 Apr 2006
Henry Jill M, Camahort Raymond, Rice Douglas A, Florens Laurence, Swanson Selene K, Washburn Michael P, Gerton Jennifer L
Abstract excerpt
During meiosis, each chromosome must pair with its homolog and undergo meiotic crossover recombination in order to segregate properly at the first meiotic division. Recombination in meiosis in Saccharomyces cerevisiae relies on two Escherichia coli recA homologs, Rad51 and Dmc1, as well as the more recently discovered heterodimer Mnd1/Hop2. Meiotic recombination in S. cerevisiae mnd1 and hop2 single mutants is...
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