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Article

Gray matter volumetric correlates of the polygenic risk of depression: A study of the Human Connectome Project data.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Oct 2024

Fu Xiaoya, Chen Yu, Luo Xingguang, Ide Jaime S, Li Chiang-Shan R

Abstract excerpt

Genetic factors confer risks for depression. Understanding the neural endophenotypes, including brain morphometrics, of genetic predisposition to depression would help in unraveling the pathophysiology of depression. We employed voxel-based morphometry (VBM) to examine how gray matter volumes (GMVs) were correlated with the polygenic risk score (PRS) for depression in 993 young adults of the Human Connectome...

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Identifiers

PMID: 38936229
DOI: 10.1016/j.euroneuro.2024.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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