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Article

Causal links between obesity, lipids, adipokines, and cognition: a bidirectional Mendelian-randomization analysis.

Frontiers in endocrinology - 1 Jan 2025

Gong Meng, Liu Haichao, Liu Zhixiang, Wang Yongshen, Qi Shiyi, Guo Hong, Jin Song

Abstract excerpt

Background: The aim of this study was to explore the genetic level association between obesity, lipids, adipokines, and cognitive ability using bidirectional Mendelian randomization (MR) strategies. Methods: Summary data for three obesity indicators [body mass index (BMI), body fat percentage (BFP) and waist-hip ratio (WHR)], three lipid indicators [HDL cholesterol (HDL), LDL cholesterol (LDL) and triglycerides...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39996061
DOI: 10.3389/fendo.2025.1439341
PMCID: PMC11849047

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