Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association Between Plasma LRG1 and Lower Cognitive Function in Asians With Type 2 Diabetes Mellitus.

The Journal of clinical endocrinology and metabolism - 13 Aug 2024

Low Serena, Moh Angela, Pandian Bhuvaneswari, Tan Xin Li, Pek Sharon, Zheng Huili, Ang Keven, Tang Wern Ee, Lim Ziliang, Subramaniam Tavintharan, Sum Chee Fang, Lim Su Chi

Abstract excerpt

CONTEXT: Leucine-rich α-2-glycoprotein 1 (LRG1) has been implicated in the pathogenesis of diabetic complications, but its association with cognitive function remains unclear. OBJECTIVE: Our primary objective is to investigate the longitudinal association between LRG1 and cognitive function in patients with type 2 diabetes mellitus (T2DM). Secondarily, we determine the causal relationship using Mendelian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cognition
Share to Cognitive Dysfunction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Glycoproteins

Share to Longitudinal Studies

Share to Mendelian Randomization Analysis

Share to Pulse Wave Analysis

Share to Vascular Stiffness

Source

Identifiers

PMID: 38170213
DOI: 10.1210/clinem/dgad768

Genes

LRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association Between Plasma LRG1 and Lower Cognitive Function in Asians With Type 2 Diabetes Mellitus.PMID 38170213Read ↗

Association of Genetic Variants for Plasma LRG1 With Rapid Decline in Kidney Function in Patients With Type 2 Diabetes.Semantic proximity Read ↗

Relationship Between Glycemia and Cognitive Function, Structural Brain Outcomes, and Dementia: A Mendelian Randomization Study in the UK Biobank.Semantic proximity Read ↗

Causal Effects of Type 2 Diabetes and Glycemic Traits on Dementia and Stroke: A Mendelian Randomization Study including Imaging EndpointsSemantic proximity Read ↗

Type 2 diabetes, glycaemic traits, structural brain capacity and cognitive function: A Mendelian randomization analysis.Semantic proximity Read ↗

The relationship between glycaemia, cognitive function, structural brain outcomes and dementia: A Mendelian randomization study in the UK BiobankSemantic proximity Read ↗

Type 2 Diabetes and Cognitive Status in the Health and Retirement Study: A Mendelian Randomization ApproachSemantic proximity Read ↗

Identification of adipose tissue‐derived exosomal micro RNA as a novel causal biomarker for cognitive impairment in type 2 diabetes mellitus: Triangulating evidence from Mendelian randomization and multicentre population studiesSemantic proximity Read ↗

Associations of cardiovascular risk factors and lifestyle behaviors with neurodegenerative disease: a Mendelian randomization study.Semantic proximity Read ↗

The causal effect of HbA1c on white matter brain aging by two-sample Mendelian randomization analysisSemantic proximity Read ↗

Mendelian randomization of dyslipidemia on cognitive impairment among older AmericansSemantic proximity Read ↗

High Body Mass Index as a Causal Risk Factor for Vascular-Related Dementia: A Mendelian Randomization Study.Semantic proximity Read ↗

Diabetes mellitus, glycemic traits, and cerebrovascular disease: a Mendelian randomization studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.