Article

Diabetes mellitus, glycemic traits, and cerebrovascular disease: a Mendelian randomization study

2019-12-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Type 2 diabetes mellitus (T2D) is an established risk factor for cerebrovascular disease but the mechanisms underlying this association remain elusive. Disentangling the causal effects of T2D, hyperglycemia, and pre-diabetic phenotypes (insulin resistance, β-cell dysfunction) on major etiological stroke subtypes (ischemic stroke, intracerebral hemorrhage, ischemic stroke subtyp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 105bf59f-e823-51b8-83ca-59794b58aa80
DOI: 10.1101/2019.12.27.19015834

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Diabetes mellitus, glycemic traits, and cerebrovascular disease: a Mendelian randomization studyDOI 10.1101/2019.12.27.19015834Read

Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease: A Mendelian Randomization Study.Semantic proximity Read

Causal Effects of Type 2 Diabetes and Glycemic Traits on Dementia and Stroke: A Mendelian Randomization Study including Imaging EndpointsSemantic proximity Read

Differential ischemic stroke risk linked to novel subtypes of type 2 diabetes: insights from a Mendelian randomization analysis.Semantic proximity Read

Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study.Semantic proximity Read

Cardiovascular diseases consequences of type 1, type 2 diabetes mellitus and glycemic traits: A Mendelian randomization study.Semantic proximity Read

Polygenic Susceptibility to Diabetes and Poor Glycemic Control in Stroke SurvivorsSemantic proximity Read

Causal effect of Insulin Resistance on Small Vessel Stroke and Alzheimer's Disease: A Mendelian Randomization AnalysisSemantic proximity Read

Causal Impact of Type 2 Diabetes Mellitus on Cerebral Small Vessel DiseaseSemantic proximity Read

Shared Genetic Architecture and Causal Relationship Between Diabetes, Glycemic Traits, and Cerebral Small Vessel DiseaseSemantic proximity Read

Data-driven subtypes of type 2 diabetes mellitus and risk of dementia, stroke, and brain structural changes in the UK BiobankSemantic proximity Read

Genetically predicted type 2 diabetes mellitus mediates the causal association between plasma uric acid and ischemic stroke.Semantic proximity Read

Causal effect of insulin resistance on small vessel stroke and Alzheimer's disease: A Mendelian randomization analysis.Semantic proximity Read