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Article

Mouse and human immune responses share neutralization epitopes of HAstV-VA1.

Journal of virology - 23 Jul 2024

Ramírez-Bello Inci, López Tomás, Espinosa Rafaela, Ghosh Anisa, Green Kassidy, Riaño-Umbarila Lidia, Gaspar-Castillo Carlos, Aguilera-Flores Catalina, Alpuche-Aranda Celia M, López Susana, DuBois Rebecca M, Arias Carlos F

Abstract excerpt

Astroviruses are highly divergent and infect a wide variety of animal hosts. In 2009, a genetically divergent human astrovirus (HAstV) strain VA1 was first identified in an outbreak of acute gastroenteritis. This strain has also been associated with fatal central nervous system disease. In this work, we report the isolation of three high-affinity neutralizing monoclonal antibodies (Nt-MAbs) targeting the capsid...

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Share to Antibodies, Monoclonal
Share to Antibodies, Neutralizing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibodies, Viral

Share to Astroviridae Infections

Share to Capsid Proteins

Share to Epitopes

Share to Mamastrovirus

Share to Neutralization Tests

Source

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Identifiers

PMID: 38916399
DOI: 10.1128/jvi.00971-24
PMCID: PMC11323900

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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