Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation of Neutralizing Monoclonal Antibodies to Human Astrovirus and Characterization of Virus Variants That Escape Neutralization

22 Oct 2018

Abstract excerpt

Human astroviruses (HAstVs) are common etiological agents of acute gastroenteritis in children, the elderly, and immunocompromised patients; some virus strains have also been associated with neurological disease. Despite their medical importance, the study of these pathogens has advanced at a slow pace. In this work, we produced neutralizing antibodies to the virus and mapped the epitopes they recognize on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Hepatitis Viruses Studies and Epidemiology
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30355681
DOI: 10.1128/jvi.01465-18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation of Neutralizing Monoclonal Antibodies to Human Astrovirus and Characterization of Virus Variants That Escape NeutralizationPMID 30355681Read ↗

Structure of a Human Astrovirus Capsid-Antibody Complex and Mechanistic Insights into Virus Neutralization.Semantic proximity Read ↗

Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralizationSemantic proximity Read ↗

Antigenic determinants of HAstV-VA1 neutralization and their relevance in the human immune responseSemantic proximity Read ↗

Mouse and human immune responses share neutralization epitopes of HAstV-VA1.Semantic proximity Read ↗

Structural Basis for Escape of Human Astrovirus from Antibody Neutralization: Broad Implications for Rational Vaccine Design.Semantic proximity Read ↗

Entry and egress of human astroviruses.Semantic proximity Read ↗

Structural, Mechanistic, and Antigenic Characterization of the Human Astrovirus CapsidSemantic proximity Read ↗

Structure and antigenicity of the divergent human astrovirus VA1 capsid spike.Semantic proximity Read ↗

Structural Insights into the Human Astrovirus CapsidSemantic proximity Read ↗

Characterization of a Human Astrovirus Serotype 2 Structural Protein (VP26) That Contains an Epitope Involved in Virus NeutralizationSemantic proximity Read ↗

Astrovirus PathogenesisSemantic proximity Read ↗

Astrovirus Biology and PathogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.