Article
Structure and antigenicity of the divergent human astrovirus VA1 capsid spike.
PLoS pathogens - 1 Feb 2024
Ghosh Anisa, Delgado-Cunningham Kevin, López Tomás, Green Kassidy, Arias Carlos F, DuBois Rebecca M
Abstract excerpt
Human astrovirus (HAstV) is a known cause of viral gastroenteritis in children worldwide, but HAstV can cause also severe and systemic infections in immunocompromised patients. There are three clades of HAstV: classical, MLB, and VA/HMO. While all three clades are found in gastrointestinal samples, HAstV-VA/HMO is the main clade associated with meningitis and encephalitis in immunocompromised patients. To...
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