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Structural Insights into the Human Astrovirus Capsid

1 May 2021

Abstract excerpt

Astroviruses (AstVs) are non-enveloped, positive single-stranded RNA viruses that cause a wide range of inflammatory diseases in mammalian and avian hosts. The T = 3 viral capsid is unique in its ability to infect host cells in a process driven by host proteases. Intercellular protease cleavages allow for viral egress from a cell, while extracellular cleavages allow for the virus to enter a new host cell to...

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PMID: 34062934
DOI: 10.3390/v13050821

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