Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structure of a Human Astrovirus Capsid-Antibody Complex and Mechanistic Insights into Virus Neutralization.

Journal of virology - 15 Jan 2017

Bogdanoff Walter A, Campos Jocelyn, Perez Edmundo I, Yin Lu, Alexander David L, DuBois Rebecca M

Abstract excerpt

Human astroviruses (HAstVs) are a leading cause of viral diarrhea in young children, the immunocompromised, and the elderly. There are no vaccines or antiviral therapies against HAstV disease. Several lines of evidence point to the presence of protective antibodies in healthy adults as a mechanism governing protection against reinfection by HAstV. However, development of anti-HAstV therapies is hampered by the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Neutralizing
Share to Antibody Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Capsid

Share to Capsid Proteins

Share to Mamastrovirus

Share to Neutralization Tests

Share to Single-Chain Antibodies

Share to Virion

Source

Open in PubMed Open full text

Identifiers

PMID: 27807234
DOI: 10.1128/JVI.01859-16
PMCID: PMC5215351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structure of a Human Astrovirus Capsid-Antibody Complex and Mechanistic Insights into Virus Neutralization.PMID 27807234Read ↗

Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralizationSemantic proximity Read ↗

Structural Basis for Escape of Human Astrovirus from Antibody Neutralization: Broad Implications for Rational Vaccine Design.Semantic proximity Read ↗

Isolation of Neutralizing Monoclonal Antibodies to Human Astrovirus and Characterization of Virus Variants That Escape NeutralizationSemantic proximity Read ↗

Structural, Mechanistic, and Antigenic Characterization of the Human Astrovirus CapsidSemantic proximity Read ↗

Crystal Structure of the Avian Astrovirus Capsid SpikeSemantic proximity Read ↗

Structure and antigenicity of the divergent human astrovirus VA1 capsid spike.Semantic proximity Read ↗

Structural Insights into the Human Astrovirus CapsidSemantic proximity Read ↗

Mouse and human immune responses share neutralization epitopes of HAstV-VA1.Semantic proximity Read ↗

Antigenic determinants of HAstV-VA1 neutralization and their relevance in the human immune responseSemantic proximity Read ↗

Structure of the divergent human astrovirus MLB capsid spikeSemantic proximity Read ↗

Crystal structure of the human astrovirus capsid spikeSemantic proximity Read ↗

Crystal Structure of the Human Astrovirus Capsid ProteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.