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Article

Structure of the divergent human astrovirus MLB capsid spike

22 Nov 2022

Abstract excerpt

Despite their worldwide prevalence and association with human disease, the molecular bases of human astrovirus (HAstV) infection and evolution remain poorly characterized. Here, we report the structure of the capsid protein spike of the divergent HAstV MLB clade (HAstV MLB). While the structure shares a similar folding topology with that of classical-clade HAstV spikes, it is otherwise strikingly different. We...

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PMID: 36417907
DOI: 10.1016/j.str.2022.10.010

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