Article
Establishment of human induced pluripotent stem cell line MURAi001-A from skin fibroblasts of a patient carrying a c.4404A > G mutation in the TET1 gene.
Stem cell research - 1 Sept 2024
Tangprasittipap Amornrat, Innachai Pawarit, Chumchuen Sukanya, Chiangjong Wararat, Jinawath Natini, Sirachainan Nongnuch, Hongeng Suradej
Abstract excerpt
Ten-Eleven Translocation methylcytosine dioxygenase 1 (TET1) is known to play a broad tumor suppressor role through demethylating and activating tumor suppressor genes. TET1 missense mutations are previously reported in many types of leukemia. Here, the human induced pluripotent stem cell line MURAi001-A was generated from skin fibroblasts derived from a 56-year-old female patient carrying the TET1 gene mutation...
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